Brits won't have to wait long to get their hands on the HTC One Max. Vodafone UK says that it will be offering the gigantic smartphone this week as a carrier exclusive in the country; customers can pick it up for �49 if they're willing to subscribe to a �47 monthly plan. An unlocked version is also ...It's a role play based off the warriors cats books
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BEIRUT (AP) — A general director of Doctors Without Borders called Tuesday for greater access for humanitarian aid to Syrians suffering in their country's civil war, and urged the international community to show the same urgency to help them as it did to address dismantling Syria's chemical weapons stockpile.
The Syrian conflict, which began as a largely peaceful uprising against President Bashar Assad in March 2011, has triggered a humanitarian crisis on a massive scale, killing more than 100,000 people, driving nearly 7 million more from their homes and devastating the nation's cities and towns. With the country now carved up into rebel- and regime-controlled areas, providing desperately needed food and medical aid has become a colossal — and dangerous — task.
"You have an industrial-scale war, but you have a very kind of small-scale humanitarian response," said Christopher Stokes, a general directors for Doctors Without Borders. "There is a recognition that greater humanitarian access is needed for life-saving assistance, but at the same time we don't see the mobilization."
The United Nations Security Council issued an appeal in early October for immediate access to all areas of the country to deliver humanitarian aid, including across conflict lines. Still, organizations that provide assistance continue to struggle to reach all the people who need it.
Stokes said the aid community has long been told that it's impossible to grant full access to all regions affected by the fighting, and that "one side is always blaming the other" for the impasse.
But the recent agreement to grant international inspectors unfettered access to every site linked to Syria's chemical weapons program "has shown is that it is possible, if the international political willingness is there, to grant access and free movement to aid agencies to go into these enclaves," Stokes said.
"Cease-fires could be organized as was done to allow chemical weapons inspectors in, they could be organized to allow in medical convoys," he said.
Doctors Without Borders says it currently runs six field hospitals in rebel-held areas, and supports 70 medical facilities in contested areas of the country and regions controlled by the government or the rebels.
The Syrian government has not granted the group permission to work in the country, so it is forced to bring in supplies surreptitiously — a high-risk job that Stokes said has become harder.
In the past, it would take a few days to get supplies brought in from abroad into the clinics, he said, whereas now it can take weeks. "There are more checkpoints, and it's harder and harder to get supplies in," he said.
On the ground, the conflict has shown no sign of easing, even on Tuesday as Muslims celebrated the holiday known as Eid al-Adha, or the Feast of Sacrifice.
In the village of Yabroud, several dozen miles north of the capital, assailants detonated explosives on the roofs of Our Lady's Church and the Church of Helena and Constantine, Syria's SANA state news agency reported.
The explosions damaged the crosses, SANA said. It said attempts to detonate more bombs outside the two churches were foiled.
The Britain-based Syrian Observatory for Human Rights activist group confirmed that several explosions went off, damaging the churches.
There was no claim of responsibility, though SANA blamed "terrorists," the regime's term for rebels. Assad has drawn support from Syria's ethnic and religious minorities, including Christians. The rebel movement is dominated by Sunni Muslims, who are a majority in Syria.
In regime attacks, warplanes bombed targets in the village of Latamneh in the central province of Hama, killing at least three children, the Observatory said. The government also bombed areas of the Eastern Ghouta district, near Damascus, and the southern city of Daraa.
As the fighting continued, Assad attended holiday prayers in a Damascus mosque. Syrian state TV showed him sitting cross-legged on the floor, in the front row of worshippers. Assad continues to appear in public, apparently to send a message of "business as usual" even as large parts of Syria lie in ruins.
Meanwhile, Syrian refugees marked a subdued holiday in the Zaatari tent camp in Jordan. The camp is home to more than 120,000 refugees and has turned into Jordan's fifth-largest city.
A few children bought toys from shops in the camp, as is customary during the holiday, and men attended special Eid prayers, though the refugees said there's no joy in the holiday.
"We feel bad, we feel bad because everyone here has lost his home and family members and his money," said Ibrahim Oweis, a refugee from Damascus.
___
Associated Press writers Maamoun Yousef in Cairo and Jamal Halaby in Amman, Jordan, contributed to this report.
Kickstarter's world conquest continues: following a Canadian launch in the summer, the crowdfunding service is now available in Australia and New Zealand. Creators in both countries can start building their projects today, and launch as soon as November 13th. Locals can accept pledges from anywhere on the planet, although their backers will have to pay through the Kickstarter website rather than Amazon Payments. If you're eager to learn the ropes, the company is hosting its first workshops for the region between October 27th and November 5th. There's no word of expansion to other countries, but it's clear that Kickstarter's international rollout is gathering steam.
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Could popcorn be the best ad-blocker?
COLOGNE, Germany – Chewing popcorn while watching cinema ads could make us immune to the brand message.
That's the finding of a new study by researchers at Cologne University, who tested the impact of cinema advertising on popcorn-munching moviegoers.
STORY: Shutdown Special: AMC Will Hand Out Free Popcorn to Federal Employees
The researchers invited participants to watch a film in a cinema preceded by a series of ads for new, unknown products. Half the audience was given free popcorn to eat during the ads; the others got a small sugar cube that dissolved in their mouths within a minute.
A week after the screening, the researchers tested the participants to analyze the effect of the cinema ads.
While viewers who only received sugar were more likely to recognize and purchase one of the new brands presented in the movie commercials, the popcorn munchers were less likely to do so.
The effect was significant. Only 40 percent of popcorn eaters chose to buy one of the newly advertised products a week later, while fully 65 percent of the non-chewers did so.
Published in the Journal of Consumer Psychology under the title "Popcorn in the Cinema: Oral Interference Sabotages Advertising Effects," the study is based on a new psychological theory about how the brain absorbs brand messages.
STORY: Analyst: Movie Theater Chains Should Focus on Customer Satisfaction, Not Popcorn Profits
According to the theory, when we are introduced to a new brand name, our lips and tongue begin to subconsciously simulate the pronunciation of the name. Each time the brand is mentioned, our brain practices the name with a sort of “inner speech,” going through the motions the mouth would need to pronounce the name.
Chewing, the researchers found, disrupted this inner speech.
“The brain is so busy with the act of chewing that it does not have the space to do this subconscious articulation,” Sascha Topolinski, one of the study's researchers, told THR. “The brand name gets blocked out.”
The findings suggest popcorn machines and candy counters in cinema foyers could be counterproductive. “Selling candy in theaters undermines advertising effects, which contradicts present marketing strategies,” Topolinski said.
But he added that the “popcorn effect” only applies to new brands.
“An ad for Marlboro, for example, is fine,” he said (cigarette ads are still legal in Germany), “because the brand name is well known and the ad just conveys a certain feeling about the brand, the Wild West or whatever. But novel brands, say for Internet companies with odd names like Zalando -- it could be a problem.”
He suggests advertisers should try to prevent candy and popcorn being sold until after the ad roll.
So far, however, there's been no response from the advertising industry to the Cologne study.
“I guess they just need time to digest it,” Topolinski said.
Elephants understand the human gesture of pointing, new research suggests.
The ability is even more impressive given that the animals received no training to understand the gesture and have never been domesticated.
"By showing that African elephants spontaneously understand human pointing, without any training to do so, we have shown that the ability to understand pointing is not uniquely human but has also evolved in a lineage of animal very remote from the primates," study co-author Richard Byrne of the University of St Andrews said in a statement.
The new finding gives elephants membership in a select club that includes dogs, cats and bottlenose dolphins. Chimpanzees that have lived with humans can be trained to follow a point, but wild chimps typically fare worse than dogs at understanding human gestures. [5 Animals With a Moral Compass]
Byrne and his colleague Anna Smet, also of St. Andrews, studied a group of 11 African elephants that took tourists on rides near Victoria Falls, on the border of Zambia and Zimbabwe. The animals had been trained to follow vocal commands, but had never learned pointing.
The team hid tasty morsels of food in several containers, then pointed to the correct bin to direct elephants to the food.
The elephants went to the correct food container two-thirds of the time, significantly above chance. All told, five out of 11 of the elephants consistently went to the right container. In contrast, 1-year-old children typically get it right about 70 percent of the time.
Even more impressive, many of the pachyderms chose the correct bin from the first try.
"What really surprised us is that they did not apparently need to learn anything. Their understanding was as good on the first trial as the last, and we could find no sign of learning over the experiment," Byrne said.
Those elephants born in captivity or bred for more human contact performed no better at the task.
Though elephants make other gestures with their trunks, no one knows whether those gestures are parallel to pointing.
The findings suggest that elephants' ability to follow a point may arise from their social natures. Elephants live in large groups and display many emotional behaviors, including marking the gravesites of lost pack members and weeping for their dead. Elephants also recognize themselves in a mirror, a hallmark of animals with sociality and empathy.
"What elephants share with humans is that they live in an elaborate and complex network in which support, empathy, and help for others are critical for survival. It may be only in such a society that the ability to follow pointing has adaptive value, or, more generally, elephant society may have selected for an ability to understand when others are trying to communicate with them, and they are thus able to work out what pointing is about when they see it," Byrne said.
The research was published today (Oct. 10) in the journal Current Biology.
Follow Tia Ghose on Twitter and Google+. Follow LiveScience @livescience, Facebook & Google+. Original article on LiveScience.
In this week’s episode of Ask A VC, we have Greylock’s newest partner, Simon Rothman, joining us in the studio. You can submit questions for our guests either in the comments or here and we’ll ask them during the show.
Rothman, who was recently promoted from EIR to Partner on Greylock’s consumer investment team, was formerly at eBay. He joined eBay in 1999 when it was still a small, U.S. collectibles auction business and helped scale eBay to nearly 200 million users generating over $40 billion in merchandise sales. While at eBay, Rothman led U.S. operations and also founded eBay Motors, which he built into a $14 billion a year global business. Following eBay he also founded Glyde, an e-commerce marketplace for electronics and more. And Rothman served as a board member of and adviser to Tesla Motors.
With Greylock’s new $100 million commitment to investing in marketplaces, we’re curious to hear where Rothman is bullish when it comes to networks.
Please send us your questions for Rothman here or put them in the comments below!
Simon joined Greylock in 2011 as an Executive-in-Residence and was promoted to Partner in 2013. He invests in entrepreneurs building consumer networks and platforms. His area of focus includes network effects businesses, transaction-based startups, and mobile apps with a specialty around marketplaces. He has served as an advisor to many marketplaces and networks including Lyft, Wanelo, Poshmark, Tango, and others. Simon is also leading Greylock’s $100 million commitment to marketplace investments. Simon is an early pioneer of online...
Greylock partners with entrepreneurs to help them build market-leading businesses. Over the past 45 years the firm has worked with hundreds of companies, 150 of which have gone on to IPOs and 100 of which have gone on to profitable M&A events. Such companies include Ascend Communications, CheckFree, CipherTrust, Constant Contact, Continental Cable, Decru, Data Domain, DoubleClick, Farecast, Internet Security Systems, Ikanos, Legato, Media Metrix, Millennium Pharmaceuticals, Openwave, Open Market, OutlookSoft, Polyserve, Red Hat, RightNow Technologies, Success Factors, Tellabs,...
The British National Crime Agency has secured its first conviction following an investigation by the agency's National Cyber Crime Unit (NCCU).
Launched last week as a replacement for the UK's Serious Organised Crime Agency, the NCA is being positioned as a single law enforcement agency that will be responsible for leading the national response to organized crime—this covers everything from cross-border criminal networks to cybercrime, as well as tracking down child sex abusers using the Internet to target children.
The NCCU is a combination of the cybercrime-fighting function that was built up under SOCA and the Metropolitan Police's e-crime unit, which was brought in under the NCA's control after building up a strong reputation in recent years.
Olukunle Babatunde, 27, of Croydon, South East London, was sentenced to serve five years and six months at Inner London Crown Court, after pleading guilty to a number of offenses including conspiracy to defraud banks, financial institutions, and their customers.
He was arrested in connection with an ongoing operation, investigating the distribution of stolen financial data obtained by means of "organized international crime." Babatunde sent out rogue phishing emails in the hope that customers would give up their banking details—which could be sold on the black market or used directly.
The agency has said that if Babatunde had been successful in his phishing operation he could have stolen nearly $1.2 million.
"This is an excellent result built on the joint working of precursor agencies and has involved the examination of a large number of data, resulting in 765 victim accounts being identified," said Andy Archibald, head of the NCCU."The National Crime Agency will continue to share information and intelligence with regards to serious and organized cyber crime, ensuring those who pose a threat to the public are identified and held accountable for their actions."
August 3, 2013 at 6:18 am
by Bruce Strand, Sports Editor
Randy Ronning was back at his post running the Elk River Open this past weekend, almost as though nothing had happened.
Less than a month earlier, Ronning spent three days unconscious in an intensive care unit.
The coach of eight Elk state tournament tennis teams and the 2012 state champions, a robust picture of health and fitness at age 60, he was almost lost due to a strange reaction to some toxic substance July 8.
Randy Ronning
?It gave me a new perspective on things. That?s for sure,? reflected Ronning with a grim smile.
That day, Ronning was resealing a driveway that he installed five years ago. He had resealed an older driveway several times without incident. Figuring he might as well do a complete job while he was at it, he tore out the old caulking on the cement apron at the end of driveway.
He suddenly got dizzy, went inside to lay down for 20 minutes and felt better. He completed the driveway job and did some yard work, but after a few hours, felt pain and swelling in his jaw.
The next morning he went to urgent care, where they recommended an antibiotic. He called a replacement for his tennis lessons and went to bed. By 5:30 p.m., his throat and face were so swollen that breathing was difficult.
Back at urgent care, his doctor, alarmed this time, directed him to take an ambulance to the emergency room. Ronning said, ?Well, my wife can drive me,? but the doctor replied, bluntly, ?You might not make it.?
Apparently mold, or a toxic substance in the caulking, or a combination of the two, caused the serious reaction, Ronning said, adding, ?We may never be sure.?
At the ICU at Mercy Hospital, they put Ronning under and didn?t wake him up until three days later.
He had a tube stuffed down his throat for a breathing passage. Having the tube removed was ?the closest thing to death I?ve ever had,? he said. ?What suffocating or drowning must be like.?
Ronning stayed at the ICU for a week. They wanted him to stay longer, but he insisted on leaving. The day he woke up, the ICU was full, but a couple days later, there were several empty beds. He commented to a doctor that a lot of people must have gotten well. But he was told, ?No, those people died,? which showed how harrowing his own experience was.
Aftereffects of the attack linger. As yet, Ronning can?t salivate and has to spray a substance into his mouth. He can?t taste food. He?s lost 20 pounds.
?My weight never fluctuated more than a pound or two in my life,? he noted.
The antibiotics caused his kidneys to shut down; they?re just now getting back to normal. Sleep was sporadic due to the dry mouth, although new medicine is helping with that. He?s been told his taste and saliva functions will return eventually.
But Ronning, who makes his living as a year-round tennis pro, along with coaching the Elks and substitute teaching, returned to the courts right away, probably his best medicine. His doctor advised against that, but the coach protested, ?I?ve got to get back. That?s what I do.?
He directed the Elk River Open for the 21st consecutive year, although for the first time, he didn?t play in it himself.
To tournament participants, Ronning was his familiar upbeat, helpful self. His own assessment: ?I?m weak, especially in the legs. I don?t really care if I gain the weight back, I just want my strength back.?
This wasn?t even the first health setback this year for Ronning, whose luck ran out suddenly after a lifetime of fitness and health. In February, finally paying a price for hundreds of thousands of serves and volleys, he needed surgery on his right rotator cuff.
He got a kick out of what the doctor told him that day: ?The good news is that you?re the most physically fit 60-year-old I?ve seen in a long time. The bad news is, you?re 60 years old.?
Source: http://feedproxy.google.com/~r/erstarnews/~3/sqUpVQIFgCw/
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Source: http://www.wrongplanet.net/postt237064.html
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New mom Snooki is down 50 pounds after giving birth to baby Lorenzo, and now she?s telling ?Extra?s? AJ Calloway how she did it. Snooks also dished on plans to go under the knife, and expand her family.
AJ hopped on a bike and joined Snooki for her favorite workout class; spinning at Flywheel Sports. Says Snooki, ?Flywheel is like spin class, but on crack? you have to go quick and crazy and you just don?t want to give up? sometimes when I do spin by myself I just give up, but in this class you just can?t.?The ?Jersey Shore? gal, who said she owes her slimmed-down figure to Flywheel and her trainer, went on to say she tries to exercise all of the time and that she is in the best shape of her life. ?Now is the best I've ever been, I have actual muscle mass so I can kick your butt.?
?
Snooki is fit and trim, but does want to do a little nip/tuck, admitting she wants to get her breasts done. Her fianc? is all for it. ?Gionni wants me to get a boob job and I want to get a boob job too, but I want to pop out all my babies first and then I'll get a boob job.?
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Snooki says she is ready to give 1-year-old Lorenzo a sibling, but has a few things to get done first. ?I would love to be pregnant now, but my house isn't done and I have to get married. I want to do it the right way for the next one.?
Source: http://www.extratv.com/2013/08/01/snooki-talks-weight-loss-boob-jobs-and-more-babies/
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Source: http://www.nbcnews.com/video/cnbc/52631644/
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Everyone cringes at the thought of tuning the big 4-0. But why does it have to be so scary? With the right amount confidence and exercise, anyone can look ten years younger.
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The first such pilot kicked off in Kenya earlier this year as part of the 4Afrika initiative, but the company has already expanded it to Tanzania, and now to South Africa.
The program is aimed at finding new means to provide broadband Internet connectivity at a lower cost to people in this region. White spaces refers to unused frequencies for television broadcasters, which can be harvested to deliver such services to users.As ZDnet notes, Microsoft has already unveiled plans to make use of such white spaces and solar-based stations so as to offer cheap wireless services to five schools in the Limpopo province in South Africa.
Furthermore, the company is said to plan more than simply offering such services, and that it will also bring Windows-based tablets and projectors to these schools, while offering laptops and training to teachers there. Solar panels to offer power sources for charging devices will also be available.
?Technology holds enormous potential for many aspects of development, but it is particularly key to areas such as education and healthcare,? Mteto Nyati, managing director of Microsoft South Africa, said.
?Reducing the cost of broadband access means millions more South Africans will get online. This will create new opportunities for education, healthcare, commerce and the delivery of government services across the country.?
The project is aimed at offering wireless services for as low as $2-$5 (?1.5 ? ?3.75) per month, for 4Mbps of uncapped usage. At the moment, ISPs charge for around $35 (?26) per month for 1Mbps ADSL services.
Nyati also confirmed plans to make similar white space broadband available for users in other areas, through a partnership with an established ISP provider.
?We see ourselves as an enabler, not a provider. We are not in the telecoms space. I don't think you'll see us becoming a network provider,? he concluded.
Source: http://news.softpedia.com/news/Microsoft-Announces-White-Spaces-Pilot-in-South-Africa-371839.shtml
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Jonnie Peacock suffered a shock defeat in the T43/44 100metres at the London Anniversary Games.
The new world champion was beaten into third place by rivals Alan Oliveira, who set a new world record of 10.57seconds, and Richard Browne, who had beaten Peacock?s previous world record during the week in Lyon.
Peacock looked tired after his exertions at the IPC world championships, where he beat adversary Browne of the USA to the T44 crown.
Brazilian Oliveira is in the T44 class so does not normally face Peacock but set an amazing new world mark at the Olympic Stadium.
Only two of the nine runners failed to set a personal best in what was a lightning-quick race.
Peacock, although third, knocked a hundredth of a second off his own PB.
However, he will not be too disappointed having added the world title to his Paralympic crown in midweek.
MORE: Hannah Cockcroft to attempt double in Rio
MORE: Alan Oliveria sets new 200m world record in Lyon ? then proposes to girlfriend
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The fiery crash landing of a Korean jetliner at the San Francisco International Airport late Saturday morning has left at least two people dead, and up to 70 injured, according to NBC Bay Area station KNTV. Hospitals say some of the injured are critical. NBC's Lester Holt reports.
By Erin McClam and Daniel Arkin, NBC News
A Boeing 777 jetliner with 307 people on board crashed and caught fire at San Francisco International Airport on Saturday after a flight across the Pacific Ocean from South Korea. Two people were killed and scores injured, authorities said.
The plane, Asiana Airlines Flight 214 from Seoul, apparently hit the lip of the seawall that separates the runway from San Francisco Bay, sources told NBC News, then slammed into the ground and skidded down the runway before coming to rest in an adjacent field, its tail sheared off and the fuselage spewing black smoke. Photos and video from the scene showed passengers sliding down the emergency chutes and walking away.
Despite the deaths and scores of injuries -- many of them serious -- San Francisco Mayor Edwin Lee said at a evening news conference that "This could have been much worse."
Federal investigators said it was too early to determine a cause.?A representative of the National Transportation Safety Board arrived on scene late Saturday and took control of the investigation.
The sources who spoke with NBC News said the pilot did not make a distress call before landing. The plane crashed in favorable weather ? partly cloudy skies and light wind.
Joanne Hayes-White, the San Francisco fire chief, said there were 307 people on board ? 291 passengers and 16 crew -- and all had been accounted for. Authorities said 182 people were taken to one of nine Bay Area hospitals, including 49 with serious injuries. Hospitals reported that the injuries included burns and fractures.
San Francisco Mayor Edwin Lee thanks the first responders of the Asiana Airlines crash and says "this could have been much worse."
She said first-responders who arrived at the jet saw a handful of survivors emerging from the bay.
?We did observe some of the passengers coming out of the water. But the plane certainly was not in the water. There was a fire on the plane, so the assumption might be that they went near the water?s edge which is very shallow to maybe douse themselves with water.?
The bodies of the two people who were killed were found on the runway, according to Hayes-White.
South Korea's transport ministry said the two who died were Chinese citizens.
Benjamin Levy, who was on the plane, described hearing a lot of screaming after the landing. He told NBC Bay Area that he also saw many head injuries, but that most of the passengers appeared to make it off the plane safely. Fire crews sprayed water and retardant foam to douse the flames.
?We were approaching perfectly well, but we were too low,? he said. ?When the pilot realized it, he put some more gas to correct it, but it was too late, so we hit the runway pretty bad, and we started going up in the air again, and we landed pretty hard.?
Josh Edelson / AFP - Getty Images
A Boeing 777 operated by Asiana Airlines crash landed at San Francisco International Airport.
Stefanie Turner, a witness, told MSNBC that she saw the plane clip the runway with its tail, then come to rest with flames and smoke billowing from the fuselage.
?The tail was too low. Instead of coming in flat it was coming in at, I would say, maybe a 45-degree angle, with the tail far too low,? she said. ?It really went through quite a few acrobatics on the runway.?
Besides the 61 Americans, the airline said the jet carried 77 Koreans, 141 Chinese, three passengers from India, one each from Japan and Vietnam and seven whose nationalities were unknown.?
The crash ? the first involving a jumbo jet in the United States in more than a decade ? happened at 11:27 a.m. local time. It left a field of debris down the runway, beginning at the seawall that divides the runway from San Francisco Bay. Pieces of the tail could be seen among the wreckage.
An air traffic control recording captured a controller saying: ?Emergency vehicles are responding. We have everyone on the way.?
David Eun, an executive with Samsung Electronics who was on the flight, posted to his Twitter account: ?I just crash landed at SFO. Tail ripped off. Most everyone seems fine. I?m ok.? He also posted a photo that showed people walking or running away from the downed plane, including at least a half-dozen who appeared to have slid down an emergency chute.
Eun previously worked at Google and AOL. Sheryl Sandberg, a friend of his and the chief operating officer of Facebook, said that she was supposed to be on Asiana 214 with family and colleagues but that they switched to a different airline to use frequent-flier miles.
The airline said on Twitter that it was investigating and would have news as soon as possible. It offered thoughts and prayers for the passengers and crew.
The deaths are the first in an accident involving a 777, a wide-body, twin-engine jet that has been in service since 1995 and is known as the Triple-7. Before Saturday, the most serious 777 accident was in January 2008, when a British Airways flight landed short and skidded onto the runway, injuring 47 people. The jet in Saturday?s crash had been in service since 2006.
San Francisco International suspended all takeoffs and landings for four hours after the crash and said that some flights were being diverted. Two of its four runways later reopened. The airport advised passengers to check with their airlines.
President Barack Obama, at the Camp David retreat in Maryland, was made aware of the crash and was in touch with federal, state and local authorities, a White House official said.
The last crash of a jumbo jet in the United States was in November 2001, when American Airlines Flight 587, an Airbus A300-600 airliner,?crashed in a New York neighborhood. The last fatal crash of any commercial plane in the U.S. was in February 2009, when a Continental Airlines regional flight crashed into a house near Buffalo, N.Y., killing 49 people.
The flight tracking service FlightAware said that Asiana 214 flew about 10 and a half hours after taking off from Incheon airport at 5:04 p.m. local time, about half an hour late. The flight had originated in Shanghai, China.
The service identified the model as a Boeing 777-200, which has a wingspan of almost 200 feet and can carry as many as 440 people. The manufacturing company Pratt & Whitney said the plane was powered by its PW4000 engines.
Federal sources told NBC News that there was no indication of terrorism. The National Transportation Safety Board said it was sending a full team to San Francisco. Boeing said it was gathering information.
?Our thoughts are with everyone affected by today?s incident at SFO,? Boeing said on its Twitter account. ?We stand ready to assist the NTSB.?
Jay Blackman, Jonathan Dienst, Richard Esposito, Tracy Jarrett and Kristen Welker of NBC News contributed to this report. The Associated Press also contributed.
This story was originally published on Sat Jul 6, 2013 3:07 PM EDT
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Public release date: 1-Jul-2013
Share ] Contact: Jesper Ekelund
jesper.ekelund@helsinki.fi
358-503-317-987
University of Helsinki
A research group led by professor Jesper Ekelund showed that by giving a very large dose of famotidine (200 mg daily), sufficient amounts of the drug are able to penetrate the so-called blood-brain barrier to affect the histamine system in the brain.
Famotidine has been used for the treatment of heartburn since the 1980s, but at regular dosing, famotidine almost does not enter the brain at all, since the brain is protected by the blood-brain barrier. By increasing the dosage five-fold the drug is able to enter the brain and affect the histamine system.
- Already after one week the symptoms of persons suffering from schizophrenia started to decrease and after four weeks of treatment the symptoms had decreased statistically significantly. The patients that participated in the study were also positively disposed towards the treatment, says Ekelund.
Thirty persons suffering from schizophrenia participated in the study. The patients had been on sickness pension for at least five years. They were randomly divided into two groups, one which received famotidine and one which received placebo. All of the patients who took famotidine responded positively to the treatment while the symptoms of those who were on a placebo did not change.
Schizophrenia is the most common and severe psychotic disorder, and is the cause of at least half of all psychiatric hospital treatment days. No randomized, controlled trials in humans that test the effect of H2 blockade in schizophrenia have been published so far.
Innovation in psychiatric medication urgently needed
Since 1963, when the subsequent Nobel prize winner Arvid Carlsson showed that dopamine has a central role in psychosis, the so called dopamine-hypothesis has been central in psychosis. All presently available medications for psychosis are based around this principle. Since treatment response is all too often incomplete and side effects common, there is still a great, unmet medical need for medications with other mechanisms of action. Many other signaling substances have been the focus of attention, but so far, the brain histamine system has most widely been regarded as important only with regard to side effects of many psychosis medications.
- Famotidine shouldn't be used directly as treatment for schizophrenia until long-term use of a dose of this size has been proved safe. However, our study shows that the histamine system in the brain offers a novel approach to treating psychosis. This should lead to increased efforts by the pharmaceutical industry to develop medications based on this histamine-based mechanism, says Ekelund.
Famotidine works by blocking the histamine H2 receptor. There are important neurons in the brain that use histamine as their primary signaling substance. These neurons have an important role as regulators of other signaling substances. From animal research, it is known that by affecting the histamine system, one can also affect other signaling substances that are known to be involved in schizophrenia.
The project has already received international recognition. Katarina Meskanen, one of the members of Ekelunds research group, was awarded the Young Scientist Award of the SCNP (Scandinavian College of Neuropsychopharmacology) and the project has been awarded substantial funding (306,000 USD) from the Stanley foundation for follow-up studies.
###
The research group will replicate the finding through a larger, multinational study in collaboration with Karolinska Institutet in Sweden, where the study is coordinated by professor Jari Tiihonen.
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Public release date: 1-Jul-2013 Share ] Contact: Jesper Ekelund
jesper.ekelund@helsinki.fi
358-503-317-987
University of Helsinki
A research group led by professor Jesper Ekelund showed that by giving a very large dose of famotidine (200 mg daily), sufficient amounts of the drug are able to penetrate the so-called blood-brain barrier to affect the histamine system in the brain.
Famotidine has been used for the treatment of heartburn since the 1980s, but at regular dosing, famotidine almost does not enter the brain at all, since the brain is protected by the blood-brain barrier. By increasing the dosage five-fold the drug is able to enter the brain and affect the histamine system.
- Already after one week the symptoms of persons suffering from schizophrenia started to decrease and after four weeks of treatment the symptoms had decreased statistically significantly. The patients that participated in the study were also positively disposed towards the treatment, says Ekelund.
Thirty persons suffering from schizophrenia participated in the study. The patients had been on sickness pension for at least five years. They were randomly divided into two groups, one which received famotidine and one which received placebo. All of the patients who took famotidine responded positively to the treatment while the symptoms of those who were on a placebo did not change.
Schizophrenia is the most common and severe psychotic disorder, and is the cause of at least half of all psychiatric hospital treatment days. No randomized, controlled trials in humans that test the effect of H2 blockade in schizophrenia have been published so far.
Innovation in psychiatric medication urgently needed
Since 1963, when the subsequent Nobel prize winner Arvid Carlsson showed that dopamine has a central role in psychosis, the so called dopamine-hypothesis has been central in psychosis. All presently available medications for psychosis are based around this principle. Since treatment response is all too often incomplete and side effects common, there is still a great, unmet medical need for medications with other mechanisms of action. Many other signaling substances have been the focus of attention, but so far, the brain histamine system has most widely been regarded as important only with regard to side effects of many psychosis medications.
- Famotidine shouldn't be used directly as treatment for schizophrenia until long-term use of a dose of this size has been proved safe. However, our study shows that the histamine system in the brain offers a novel approach to treating psychosis. This should lead to increased efforts by the pharmaceutical industry to develop medications based on this histamine-based mechanism, says Ekelund.
Famotidine works by blocking the histamine H2 receptor. There are important neurons in the brain that use histamine as their primary signaling substance. These neurons have an important role as regulators of other signaling substances. From animal research, it is known that by affecting the histamine system, one can also affect other signaling substances that are known to be involved in schizophrenia.
The project has already received international recognition. Katarina Meskanen, one of the members of Ekelunds research group, was awarded the Young Scientist Award of the SCNP (Scandinavian College of Neuropsychopharmacology) and the project has been awarded substantial funding (306,000 USD) from the Stanley foundation for follow-up studies.
###
The research group will replicate the finding through a larger, multinational study in collaboration with Karolinska Institutet in Sweden, where the study is coordinated by professor Jari Tiihonen.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-07/uoh-ntf070113.php
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By Alastair Macdonald and Tom Perry
CAIRO (Reuters) - Mass demonstrations across Egypt on Sunday may determine its future, two and half years after people power toppled a dictator they called Pharaoh and ushered in a democracy crippled by bitter divisions.
The protesters' goal again is to unseat a president, this time their first freely elected leader, the Islamist Mohamed Mursi. Liberal leaders say nearly half the voting population - 22 million people - have signed a petition calling for change.
But with the long dominant, U.S-funded army waiting in the wings, and world powers fearing violence may unhinge an already troubled Middle East, Mursi's Muslim Brotherhood and militant allies pledge to defend what they say is the legitimate order.
Several people have been killed, including an American student, and hundreds were wounded in days of street fighting.
Mursi calls opponents bad losers backed by "thugs" from the rule of Hosni Mubarak. He is banking on the "Tamarud - Rebel!" coalition fizzling out, as other challenges in the streets have done since he took power a year ago on Sunday.
An economic crisis deepened by unrest and political deadlock may spur many less partisan Egyptians to join the rallies, due to start in the afternoon in Cairo. But many, too, are weary of turmoil and are skeptical that the opposition's demand to reset the rules of the new democracy is better than soldiering on.
U.S. President Barack Obama called on Egyptians to focus on dialogue. His ambassador to Egypt has angered the opposition by suggesting protests are not helping the economy.
Liberal leaders, fractious and defeated in a series of ballots last year, hope that by putting millions on the streets they can force Mursi to relent and hand over to a technocratic administration that can organize new elections.
"We all feel we're walking on a dead-end road and that the country will collapse," said Mohamed ElBaradei, former U.N. official, Nobel laureate and liberal party leader. "All Egypt must go out tomorrow to say we want to return to the ballot box, and build the foundations of the house we will all live in."
"CIVIL WAR"
Religious authorities have warned of "civil war". The army has said it will step in if violence gets out of control but insists it will respect the "will of the people".
Mursi, who on Saturday met the head of the military he appointed last year, interprets that to mean army support for election results. Opponents believe that the army may heed the popular will as expressed on the streets, as it did in early 2011 when the generals decided Mubarak's time was up.
That would depend on a massive turnout, which is uncertain. Islamists suspect that agents of the old order are intent on shedding blood to trigger a military intervention.
In Cairo, thousands of people gathered on Tahrir Square, the seat of the January 25 uprising of 2011, some saying they will camp out until Mursi goes. Others gathered outside the presidential palace several miles away, which was under heavy guard.
In a nearby suburban neighborhood, the Muslim Brotherhood and allies who include former militant organizations, have set up camp outside a mosque. Guarded by baton-wielding civilians in protective clothing, the Islamists say they will defend Mursi.
Both sides say they want to avoid violence but that has not prevented incidents in which the Brotherhood says several of its offices around the country have been attacked and at least five of its supporters killed in the past week.
"It will be imperative for peaceful protesters to clearly separate themselves from the thugs that use them as cover," an aide to Mursi said. "And it will be more important for the leaders calling for these protests to back away from the language of violence and demonization."
U.S. CONCERN
The United States has evacuated non-essential diplomatic staff and families and Obama said protecting U.S. missions was a priority. He was criticized at home when the ambassador to Libya was killed last year in an attack on the consulate in Benghazi.
The Egyptian army, half a million strong and financed by Washington since it backed a peace treaty with Israel three decades ago, says it has deployed to protect key installations.
Among these is the Suez Canal. Cities along the vital global waterway are bastions of anti-government sentiment. A bomb killed a protester in Port Said on Friday. Beyond the canal, in the Sinai peninsula which borders Israel and the Gaza Strip, a police general was gunned down in an ambush on Saturday.
Visiting the other end of Africa, Obama said in Pretoria: "Every party has to denounce violence ... We'd like to see the opposition and President Mursi engage in a more constructive conversation about how they move their country forward because nobody is benefiting from the current stalemate."
Mursi renewed an offer last week to include opponents in a new panel to review a controversial new constitution and has complained of a media campaign of vilification. The authorities have taken legal action against journalists and owners.
Opponents cite that among evidence that the Brotherhood, suppressed for decades under Mubarak, aims to use its organized, vote-winning power to entrench itself and its Islamic agenda deep in the state, in much the same way as the ousted leader.
Observers note similarities with protests in Turkey this month, where an Islamist prime minister with a strong electoral mandate has been confronted in the streets by angry secularists.
With much of the Arab world in turmoil after the uprisings that also brought sectarian civil war to Syria, the fate of its biggest nation may be determined by events in the coming days.
(Reporting by Asma Alsharif, Alexander Dziadosz, Shaimaa Fayed, Maggie Fick, Alastair Macdonald, Shadia Nasralla, Tom Perry and Yasmine Saleh in Cairo, Yusri Mohamed in Ismailia and Abdelrahman Youssef in Alexandria; Writing by Alastair Macdonald; Editing by Alison Williams)
Source: http://news.yahoo.com/egypt-violence-builds-american-among-dead-054530510.html
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With a week remaining until the June 25 special election for John Kerry?s former US Senate seat in Massachusetts, the two candidates met Tuesday night in a debate that set the tone for the final days of the campaign: energetic, divisive, and at times downright petty.
As the conversation swept from NSA secrets leaker Edward Snowden to the candidates? tax returns to the merits of affirmative action, Democrat Edward Markey and Republican Gabriel Gomez bickered over policy nuances that in other states might be reserved for a Democratic Party primary.
Mr. Markey told Mr. Gomez, for instance, that he was galled by the fact that the Republican did not support a ban on the sale of assault weapons or high-capacity magazines.
RECOMMENDED: Eight open US Senate seats in 2014
?You?ve been completely misrepresenting my view on gun control,? Gomez shot back, citing his own support for legislation requiring extended background checks for potential gun owners ? a bill that only four Republican senators voted for earlier this year. ?I?m the one who?s going against the NRA,? he added.
And when the debate turned to affirmative action, both candidates rushed to support the policy.
?I don?t think we?ve reached the day yet where we can say that race doesn?t play a role? in public life, Markey said, while Gomez told the audience that ?everybody should have equal opportunity to achieve the American dream.?
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That provided a strange twist to the debate, says Marc Landy, a political scientist at Boston College, because even many Democrats are skittish about supporting affirmative action and the topic has not been heavily discussed in this campaign so far. ?It?s been a very long time since I?ve heard a Republican express that kind of support,? he says.
But if the candidates? messages were sometimes hard to parse, the stylistic differences between the two were prominent. Gomez was the charmer, tugging his personal story ? as a businessman, a Navy SEAL, and an immigrant ? toward center stage on nearly every question. Meanwhile Markey, an 18-term congressman, played the policy wonk ? unshakeable in his positions, encyclopedic on his knowledge of Beltway politics.
But Gomez also displayed a new nimbleness on issues of policy, particularly national security, says Peter Ubertaccio, chairman of the political science and international studies department at Stonehill College in Easton, Mass. ?If you?ve been watching him progress since the primaries, you see there?s been a huge amount of improvement as a candidate in his ability to answer questions and not rely on canned one-liners.?
The candidates had substantive exchanges on National Security Agency surveillance ? both support prosecution of self-described whistleblower Edward Snowden ? and how best to wind down the long US-led wars in Iraq and Afghanistan.
Still, the moderator?s efforts to direct the conversation to a wide variety of policy areas didn?t stop the two men from deploying familiar refrains throughout the evening.
Markey worked to paint Gomez as wealthy and secretive, digging into him for his low tax rate and for refusing to release a list of clients he?d worked with during his career in private equity.
?Mr. Gomez makes 10 times more than I do per year, and he paid pretty much the same tax rate,? he said.
Gomez, meanwhile, played to voter fatigue with career politicians.
?I think 37 years is enough time,? he said, referring to the nearly four decades Markey has spent in Washington as a congressman. ?I ask you to give me 17 months to see if I fit this role. If I have, reelect me, and if I haven?t vote me out.?
That?s a popular message among Gomez?s supporters as well, dozens of whom gathered outside the studios of WGBH-TV in the Boston neighborhood of Brighton, where the debate was held Tuesday afternoon. As a drizzle splattered Gomez campaign signs reading SEAL THE DEAL and NO EASY DAY, Victor Navarro, a young financial analyst and Peruvian immigrant, said he appreciated Gomez?s fresh take on Washington politics.
?This is the future of the Republican Party,? he said. ?He appeals to younger people. Ed Markey has been in Congress longer than we?ve been alive.?
Across the street, Markey campaigner John Gates said his main concern in the week leading to the election is turning out the masses of voters who have tuned out election coverage so far.
?It?s been tough to get people involved,? he said. But as he canvassed and phonebanked, he has been regularly deploying a key phrase to spook Democrats into hauling themselves to the polls next week: Scott Brown. Mr. Brown, a Republican, snatched a surprise victory from Democratic Attorney General Martha Coakley in a 2010 special election for a Senate seat.
Brown?s victory shocked Democrats in part because a Boston Globe poll the week before that election showed him down by 15 percentage points. That?s heartening news for Gomez, who trails by 13 points according to a Globe poll released over the weekend.
In fact, the Gomez campaign has already begun to spin that down-but-not-out message to its advantage. In a memo to Gomez?s staff Tuesday, Republican political strategist Curt Anderson said the candidate has been a tenacious fighter against an opponent with four times his funds and three times the number of registered voters in his party.
?With the tonnage of negative advertising that Cong. Markey and all these outside interest groups have poured into Massachusetts, one would think Markey would be running in the clear at this point,? Mr. Anderson wrote. ?But he?s not.?
Gomez himself didn?t shy away from that message. Addressing the debate?s significance, he told reporters it was a turning point for his campaign.
?You saw the beginning of the comeback of the underdog guy,? he said.
RECOMMENDED: Eight open US Senate seats in 2014
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Source: http://news.yahoo.com/last-gomez-markey-debate-distinct-styles-fuzzy-policy-132054197.html
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